Harsh direct lighting - High noon with harsh direct light will require augmented/supplemental lighting.
Cross interaction - Live action actors and virtual environments have a difficult time interacting. There are cases where this will work, for instance having a physical flashlight shine into the digital world, however these are limited at this point.
Small scale - Locations which are much smaller than that Volume’s physical size. These tend to warp and display incorrectly. In this case, a smaller more bespoke setup would be better.
Certain Special Effects - Scenes which require special effects in the scenic set which could damage the Volume such as: oil based fog, fire, and explosions.
Digital Humans/Background Actors - Scenes which require many background extras